Our Pipeline

Changing the possible for patients

We never lose sight of why our work matters – the potential to impact the lives of patients is important to everyone at Sana. We are advancing a number of innovative drug candidates with the goal of disrupting the possible for patients across a diverse set of diseases.

Pipeline


Ex Vivo Cell Engineering

Hypoimmune Technology: Donor-derived

Product Candidate Cell Type Potential Indications

SC291 (CD19)

T cells

Oncology

• Non-Hodgkin lymphoma (NHL)

• Acute lymphoblastic leukemia (ALL)

• Chronic lymphocytic leukemia (CLL)


Pre Clinical

SC262 (CD22)

T cells

Oncology


• Non-Hodgkin lymphoma (NHL)


• Acute lymphoblastic leukemia (ALL)


• Chronic lymphocytic leukemia (CLL)


Pre Clinical

SC255 (BCMA)

T cells

Oncology

Multiple myeloma


Pre Clinical

Hypoimmune Technology: Stem cell-derived

Product Candidate Cell Type Potential Indications

SC451

Islet cells

Diabetes

Type 1 diabetes


Pre Clinical

Stem cell-derived (to migrate to Hypoimmune Technology)

Product Candidate Cell Type Potential Indications

SC379

Glial progenitor cells

Central nervous system (CNS)

• Huntington’s disease

• Pelizaeus-Merzbacher disease

• Secondary progressive multiple sclerosis


Pre Clinical

In Vivo Cell Engineering

Fusogen Technology

Product Candidate Cell Type Potential Indications

SG295 (CD8/CD19)

T cells

Oncology

• Non-Hodgkin lymphoma (NHL)

• Acute lymphoblastic leukemia (ALL)

• Chronic lymphocytic leukemia (CLL)


Pre Clinical

SG239 (CD8/BCMA)

T cells

Oncology

Multiple myeloma


Pre Clinical

SG242 (CD4/CD19)

T cells

Oncology

• Non-Hodgkin lymphoma (NHL)

• Acute lymphoblastic leukemia (ALL)

• Chronic lymphocytic leukemia (CLL)


Pre Clinical

SG221 (CD4/BCMA)

T cells

Oncology

Multiple myeloma


Pre Clinical

SG233 (CD8/CD22)

T cells

Oncology


• Non-Hodgkin lymphoma (NHL)


• Acute lymphoblastic leukemia (ALL)


• Chronic lymphocytic leukemia (CLL)


Pre Clinical

SG418

Hematopoietic stem cells

Hemoglobinopathies

• Sickle cell disease

• Beta-thalassemia


Pre Clinical