Select Publications related to the Hypoimmune Platform:

  1. Survival of Transplanted Allogeneic Beta Cells with No Immunosuppression. August 2025. New England Journal of Medicine.

  2. Replacement of Beta Cells for Type 1 Diabetes. September 2025. New England Journal of Medicine.

  3. Hypoimmune islets achieve insulin independence after allogeneic transplantation in a fully immunocompetent non-human primate. March 2024. Cell Stem Cell.

  4. Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques. May 2023. Nature Biotechnology.

  5. Human hypoimmune primary pancreatic islets avoid rejection and autoimmunity and alleviate diabetes in allogeneic humanized mice. April 2023. Science Translational Medicine.

  6. Hypoimmune anti-CD19 chimeric antigen receptor T cells provide lasting tumor control in fully immunocompetent allogeneic humanized mice. April 2023. Nature Communications.

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